This dataset contains petrophysical characteristics of andesite samples (geometry, porosity, permeability) before and after a series of mechanical tests (which were conducted as part of another project). The data is presented in the publication Lamur et al., 2023 (https://doi.org/10.1038/s41598-022-26721-x). The data were collected at the University of Liverpool, analysed at the University of Liverpool and LMU Munich. All samples were collected on Colima volcano, Mexico. Experiments were conducted in 2021 and data analysed throughout 2021 and 2022. For each experiment, a rock cylinder of 25x50 mm (diameter x height) is prepared. Porosity data is calculated from sample geometry and volume measured in a helium pycnometer. Permeameter data is output automatically from the permeameter when a constant flow rate of helium gas through the sample is achieved, at which point the pressure differential and flow rate are used to calculate permeability. The values are for andesite samples from Colima volcano, pre- and post- mechanical testing. The data show the extent of changes of petrophysical properties possible by mechanical deformation in the brittle regime. Volcanic environments are often subjected to low magnitude; repetitive earthquakes that may contribute to the overall rock mass (or volcanic edifice/dome) fatigue. Understanding how such mechanical oscillations may change the characteristics of the volcanic rocks comprising the edifice can help better understanding associated hazards.