Stable isotope data of organic carbon, nitrogen and sulfur as well as trace elements are used to explore how proxies with differing residence times in seawater respond to changes in the basin’s connectivity to the open ocean. The results show that species with a short residence time, such as nitrate and rare earth elements, may be more sensitive to geologically brief fluctuations in oceanographic conditions than long-lived species like sulfate. Details about the methodology and sampling strategy can be found in Stu¨eken, E.E., Viehmann, S. and Hohl, S.V., 2023, ACS Earth and Space Chemistry, 7(7), pp.1337-1349.