The data are from a suite of friction experiments performed on simulated fault gouges comprised of clay-quartz mixtures, sheared in a direct-shear arrangement. Some experiments were performed on gouge layers comprised of adjacent patches of kaolinite-clay and quartz (i.e. heterogeneous gouge layers), whereas others were performed on homogeneous mixtures of the two materials (i.e. homogeneous gouge layers). More information on the different types of experiment is provided in the accompanying metadata for this dataset. The relative proportions of clay and quartz were varied in different experiments. All experiments were performed at an effective normal stress of 40 MPa. The sliding velocity was stepped between 0.3 and 3 microns/s every 1 mm of displacement to calculated the rate-and-state friction parameter (a-b). The evolution of shear stress was monitored with increasing displacement (up to a maximum displacement of 8.5 mm).